Sales Reps (by region/city/state/country) with different sales prices (B2B)

Sometimes distributors have an online store (with a general price) and also have sales reps working in different cities/states/countries. Every sales rep can have a different commission and price list (because of either import duties or taxes or freight).
With a dedicated login, the sales rep could manage his sales and gains (commission).
When there is a new customer (B2B) request, through the site, the sales receive an email informing the request of the customer in his region.